GORYO Chemical, Inc.
- Kenichi Maruyama
Development of fluorescent probes for quick diagnosis during cancer surgery
Goryo Chemical, Inc is developing cancer diagnostics with fluorescent probes discovered by Prof. Urano at the University of Tokyo. These probes are called “activatable fluorescent probes”. Activatable fluorescent probes can detect analytes with a high S/N ratio and brightness. The probes do not show any fluorescence if the target is absent. When these probes are applied during cancer surgery the probes will light up the cancer cells selectively within a one-minute timeframe. This would contribute to the reduction of residual cancer cells during the excision of tumors and surgery time.
Goryo Chemical, Inc. was established in 2010 in Sapporo, Hokkaido to develop fluorescent probes not only for research reagents but also for medical use.
Goryo Chemical has platform technologies of fluorescent dyes for diagnostics, which were initially developed by Urano Laboratory of the University of Tokyo. Furthermore, Goryo Chemical has the capability of synthesizing these dyes efficiently.
UTEC’s value add
UTEC connected Goryo Chemical with the University of Tokyo and has offered hands-on support including business planning, financing and recruiting.
Detection of cancer cells using gGlu-HMRG fluorescence
Human ESD (Endoscopic Submucosal Dissection) cancer samples at each reaction state with EP-HMRG (before spraying EP-HMRG (left), after 5 min (middle) and after 10 min (right))