OriCiro Genomics, Inc. (Exited)



Innovative cell-free DNA assembly and amplification technology for Synthetic Biology

Using its proprietary cell-free technologies for large DNA assembly and amplification, OriCiro Genomics provides products and services including (1) reagent kits for research, (2) co-development, and (3) technology licensing for plasmid DNA manufacturing.



OriCiro’s technology was invented by Dr. Masayuki Suetsugu of Rikkyo University, a co-founder of the company through his research under the ImPACT program funded by the Japanese government. The formation of the company was led by UTEC for the purpose of commercializing the invention as a platform technology for the emerging field of Synthetic Biology.


Cell-based cloning is widely used today for amplifying large DNA as an essential part of biotech research and development. However, it is a cumbersome and time-consuming process. OriCiro’s technology offers a solution in the form cell-free DNA amplification.
The technology allows not only the amplification of large DNA but also the amplification of sequences that are infeasible to amplify by existing methods. Furthermore, OriCiro’s technology can assemble many DNA fragments into a large DNA more efficiently than current approaches. Combining OriCiro’s assembly and amplification processes unlocks a new innovative and efficient synthesis of genome-size DNA.

UTEC’s value add

UTEC recognized the innovativeness of the technology at the very early stage of its development and led the OriCiro's startup process, including the formation of the management team. UTEC has provided support in negotiating alliances with pharmaceutical companies, building intellectual properties, and recruiting human resources.
  • Reconstruction of the E.coli genome propagation process in vitro

  • Efficient synthesis of genome-size DNA from multiple DNA fragments

  • Viscous, synthesized long-strand DNA