PORTFOLIO
PORTFOLIO COMPANIES
COMPANY PROFILE
Gene therapy for neurodegenerative disease
SOLA owns the JUMP70 platform, a gene therapy that uses AAV to express JUMP70, a fusion protein capable of bringing disease-causing proteins into close proximity with the HSP70 protein, so that HSP could refold or induce degradation of the mis-folded aggregate protein which is a cause of neurodegenerative diseases. The lead pipeline, SOL-257, is being developed for ALS, a disease caused by the aggregation of TDP-43 protein.
COMPANY STORY
Origin
SOLA Biosciences was founded in 2016 by Dr. Keizo Koya, CEO and Dr. Akinori Hishiya, CSO. Dr. Koya is a serial entrepreneur having experience in founding Strategia (which was acquired by JSI InnoMed). Dr. Hishiya has experience as a researcher at Eli Lilly, the National Center for Geriatrics and Gerontology, Georgia Medical College, Boston Biomedical Research Institute, and Strategia, Inc.
Strength
SOLA owns the JUMP70 platform, a gene therapy that uses AAV to express JUMP70, a fusion protein capable of bringing disease-causing proteins into close proximity with the HSP70 protein, so that HSP could refold or induce degradation of the mis-folded aggregate protein which is a cause of neurodegenerative diseases. The lead pipeline, SOL-257, is being developed for ALS, a disease caused by the aggregation of TDP-43 protein.
UTEC’s value add
Introduction of scientific advisers in the US or in AAV field, support capital raising, business development, and IP strategy, etc.
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JUMP70 to engage aggregated protein and HSP70
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The domain of JUMP70
STORY LIST Interviews with leaders of UTEC's portfolio companies: past and present.